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应用增殖细胞核抗原（ＰＣＮＡ）单克隆抗体Ｐｃ１０免疫组化ＡＢＣ法对８２例喉鳞癌的细胞增殖活性进行检测。结果表明，组织学恶性度高的肿瘤ＰＣＮＡ阳性细胞数明显多于恶性度低的肿瘤（Ｐ＜０．０１）。５年生存组的患者ＰＣＮＡ标记数明显低于５年内死亡组（Ｐ＜０．０１）。提示ＰＣＮＡ免疫组化标记可作为判断喉鳞癌恶性度及估计患者预后的指标。
The proliferative activity of 82 cases of laryngeal squamous cell carcinoma was detected by PC10 monoclonal antibody Pc10 immunohistochemical ABC method. The results showed that the histological malignancy was significantly higher than the number of PCNA positive tumor cells (P <0.01). The number of PCNA markers in 5-year survival group was significantly lower than that in 5-year death group (P <0.01). Tip PCNA immunohistochemical markers can be used to determine the degree of malignancy and prognosis of laryngeal squamous cell carcinoma prognosis indicators.