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目的观察晚期贲门癌介入治疗的效果。方法32例晚期贲门癌患者,采用胃动脉内化学性栓塞(GAE)20例,胃动脉内化学性灌注(GAI)12例。结果采用介入治疗,总有效率(完全缓解+部分缓解)为88%(28/32),其中GAE组完全缓解6例。生存概率在GAE组前5个月内,随时间推移变化不大,GAI组3个月内迅即下降,两种方法差异有非常显著意义(P<0.01)。不良反应以血液学毒性为主,GAE组合并有栓塞后综合征。结论介入治疗特别是GAE为治疗晚期贲门癌的有效方法。
Objective To observe the effect of interventional treatment for advanced cardiac cancer. Methods Thirty-two patients with advanced cardiac cancer were treated with intra-arterial chemical embolization (GAE) in 20 cases and intragastric artery chemical infusion (GAI) in 12 cases. Results Using interventional therapy, the total effective rate (complete remission + partial remission) was 88% (28/32), of which 6 cases were completely relieved in the GAE group. The probability of survival in the first 5 months of the GAE group did not change significantly over time, and the GAI group immediately decreased within 3 months. There was a significant difference between the two methods (P<0.01). Adverse reactions were mainly hematological toxicities, GAE combined with postembolism syndrome. Conclusion Interventional treatment, especially GAE, is an effective method for the treatment of advanced cardiac cancer.