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用外科手术方法将健康成年SD大鼠睾丸淋巴管阻断,观察阻断后不同时间睾丸间质的变化。阻断后2天,间质呈现炎症反应,炎性细胞浸润,血管扩张。阻断后6天,间质出现灶状增生,间质细胞梭化:数量增多。阻断后12天,炎症反应减轻,部分间质细胞核固缩,深染。阻断后24天,炎症反应消失,间质细胞数量减少。阻断后48天,间质改变仍未见恢复。
The lymphatic vessels of the testis of healthy adult SD rats were blocked by surgery, and the changes of testicular interstitium were observed at different times after the occlusion. Two days after the blockade, the stroma showed inflammatory reaction, inflammatory cell infiltration and vasodilation. Six days after the blockade, focal interstitial hyperplasia appeared and interstitial cell shuttling occurred: the number increased. After 12 days of blocking, the inflammatory response was alleviated, part of interstitial nuclei were pyknotic and deeply stained. 24 days after the blockade, the inflammatory response disappeared and the number of interstitial cells decreased. 48 days after blocking, interstitial changes have not yet been restored.