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Objective: To observe the influence of Buyang Huanwu Decoction (BYHWD) on the activity of blood platelet activating factor receptor (PAFR). Methods: BYHWD was administered to rabbits in vitro or in vivo and its effect on PAFR was observed by radioligand receptor binding method. Results: BYHWD tended to increase the specific binding amount of washed platelet PAFR with radioligand in vivo, which was similar to that of Ginkgo leaf extract. And in vitro, it showed an inhibition on the specific binding of washed platelet PAFR. Conclusion: BYHWD has certain effect on PAFR amount in vivo and PAFR activity in vitro.
Objective: To observe the influence of Buyang Huanwu Decoction (BYHWD) on the activity of blood platelet activating factor receptor (PAFR). Methods: BYHWD was administered to rabbits in vitro or in vivo and its effect on PAFR was observed by radioligand receptor binding method Results: BYHWD tended to increase the specific binding amount of washed platelet PAFR with radioligand in vivo, which was similar to that of Ginkgo leaf extract. And in vitro, the showed an inhibition on the specific binding of washed platelet PAFR. Conclusion: BYHWD Has certain effect on PAFR amount in vivo and PAFR activity in vitro.