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目的 综合评价血清甲胎蛋白 (AFP)与α -L -岩藻糖苷酶 (AFU)对原发性肝癌 (PHC)诊断价值。方法 测定 39例原发性肝癌 ,5例转移性肝癌 ,51例肝硬化患者的血清AFP、AFU含量。结果 PHC患者血清AFP、AFU含量明显高于其他两组 (P <0 0 0 1)。AFP、AFU诊断的阳性率分别为 74 36%和 69 2 3% ,而联合检测对PHC诊断的阳性率较单项检测有所提高 ( 84 62 % ) ,但无统计学意义 (P >0 0 5)。结论 AFP、AFU可作为原发性肝癌诊断的血清学标志物。AFP、AFU联合检测对肝癌诊断的阳性率较单项检测无明显差异。
Objective To evaluate the diagnostic value of serum alpha-fetoprotein (AFP) and α-L-fucosidase (AFU) in primary liver cancer (PHC). Methods The levels of serum AFP and AFU in 39 cases of primary liver cancer, 5 cases of metastatic liver cancer and 51 cases of liver cirrhosis were determined. Results The serum levels of AFP and AFU in PHC patients were significantly higher than those in other two groups (P < 0 01). The positive rates of AFP and AFU were 74.6% and 69.23%, respectively. The positive rate of combined detection of PHC was higher than that of single test (84.62%), but it was not statistically significant (P > 0 0 5). ). Conclusion AFP and AFU can be used as serological markers for the diagnosis of primary liver cancer. The positive rate of AFP and AFU combined detection for the diagnosis of liver cancer was no significant difference compared with single test.