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目的 探讨抑白生血糖浆对白血病化疗时骨髓的保护作用。方法 将中药方剂中的原药配成糖浆。实验组为 15 例儿童白血病用常规化疗加抑白生血糖浆治疗,对照组为15例儿童白血病人只用常规化疗。观察发热、血象、骨髓及体征 3 个月。结果 实验组在治疗中发热持续时间、Hb、WBC、恢复正常时间以及完全缓解时间均较对照组短,差异显著(P<0.05)。随访骨髓检查,治疗组骨髓抑制较对照组少(P<0.01), 差异显著。治疗中治疗组输 RBC悬液、G CSF次数较对照组少,感染次数也较对照组少,差异显著(P<0.05)。结论 抑白生血糖浆具有增强机体免疫功能、抑制白血病细胞、减轻骨髓抑制的作用。
Objective To investigate the protective effect of inhibiting white blood syrup on bone marrow in chemotherapy of leukemia. Methods The traditional Chinese medicine recipe dubbed syrup. The experimental group was 15 cases of childhood leukemia with conventional chemotherapy plus anti-leucocyte syrup, while the control group of 15 cases of childhood leukemia only conventional chemotherapy. Observation of fever, blood, bone marrow and signs of 3 months. Results The duration of fever, Hb, WBC, time to complete recovery and complete remission in experimental group were shorter than those in control group (P <0.05). Follow-up bone marrow examination, the treatment group bone marrow suppression than the control group less (P <0.01), the difference was significant. In the treatment group, the number of RBC suspension and G CSF lost in the treatment group was less than that in the control group, and the number of infection was also lower than that in the control group (P <0.05). Conclusions Inhibiting white blood syrup has the function of enhancing immune function, inhibiting leukemia cells and reducing myelosuppression.