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目的：降低吲哚拉辛消化系统副作用，满足风湿性或类风湿性关节炎患者长期使用本品的目的。方法：首先对处方中透皮吸收剂的种类及浓度、助溶剂的用量等因素进行考察，确定最优组方，按筛选出处方配制吲哚拉辛擦剂并观察临床疗效。结果：所得擦剂无刺激激性、质量可控，经临床使用总有效率达９６．５％。结论：本擦剂不仅适宜于医院小量配制，也适宜于药厂大批量生产，值得临床推广应用。
OBJECTIVE: To reduce the side effects of indolacil digestive system and to meet the purpose of long-term use of this product in patients with rheumatic or rheumatoid arthritis. Methods: Firstly, the types and concentrations of transdermal absorbent in the prescription and the amount of cosolvent were investigated to determine the optimal prescription. The indolacin capsules were prepared according to the prescriptions and the clinical efficacy was observed. Results: The resulting liniment irritation, quality control, the total effective rate of 96.5% after clinical use. Conclusion: The liniment not only suitable for the hospital a small amount of preparation, but also suitable for large-scale pharmaceutical production, worthy of clinical promotion and application.