急性非结石性胆囊炎常见于危重脓毒症患者 ,多发生在长期禁食和胆囊滞留之后 ,其发病机制不明 ,虽然以往研究已提示胆囊缺血是其中一个原因。为了确定内毒素是否会引起类似非结石性胆囊炎的组织学变化以及内毒素对胆囊动力的影响 ,进行如下实验研究。取负鼠给予大肠杆菌脂多糖 Acute non-calculous cholecystitis is common in critically ill sepsis patients, occurs after long-term fasting and gallbladder retention, the pathogenesis is unclear, although previous studies have prompted gallbladder ischemia is one of the reasons. To determine if endotoxin causes histological changes similar to non-calcific cholecystitis and the effects of endotoxin on gallbladder motility, the following experimental studies were performed. Take the possum to give E. coli lipopolysaccharide