目的分析和研究米索前列醇在临床上对产后防治出血的效果。方法我们选取2009年12月至2011年12月住院产妇70例,将其按随机分为治疗组35例与对照组35例。治疗组的产妇在分娩后采用药物200ug米索前列醇舌下含服,对照组的产妇在分娩后采用药物10u缩宫素静脉滴注,将两组产妇的产后情况进行对比。结果治疗组与对照组两组的产妇胎儿分娩后的24h内出血量减少明显(P<0.05),具有统计学意义。第三产程的时间缩短明显(P<0.05),具有统计学意义。治疗组的疗效同对照组疗效相比更为显著(P<0.05),具有统计学意义。结论药物米索前列醇在临床上应用于产妇胎儿分娩后预防出血的效果比较显著,产妇用药期间不良反应较轻,安全性与可靠性较高,值得在临床推广与应用。 Objective To analyze and study the effect of misoprostol on postpartum hemorrhage prevention and treatment. Methods We selected 70 cases of hospitalized maternal from December 2009 to December 2011. They were randomly divided into treatment group 35 cases and control group 35 cases. Maternal treatment group after delivery of 200ug misoprostol sublingual, control group of maternal intravenous injection of drug 10u oxytocin after delivery, the two groups of maternal postpartum conditions were compared. Results In the treatment group and the control group, the amount of bleeding decreased significantly within 24 hours after childbirth (P <0.05), which was statistically significant. The time of the third stage of labor shortened significantly (P <0.05), with statistical significance. The curative effect in the treatment group was more significant than that in the control group (P <0.05), which was statistically significant. Conclusion The drug misoprostol is clinically applied to the prevention of bleeding after giving birth in maternal fetus. The adverse reactions during maternal medication are lighter, and the safety and reliability are higher, which is worthy of clinical application and promotion.