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目的探讨丁苯酞氯化钠注射液治疗急性脑梗死临床疗效以及安全性。方法 64例急性脑梗死患者,随机分为对照组和治疗组,各32例。两组均给予常规治疗,治疗组在此基础上加用丁苯酞氯化钠注射液治疗。比较两组临床疗效及神经功能缺损评分(NIHSS评分)变化及不良反应发生情况。结果治疗后治疗组的NIHSS评分明显低于对照组(P<0.05);治疗组的临床疗效明显优于对照组(P<0.01);两组不良反应比较,差异无统计学意义(P>0.05)。结论丁苯酞氯化钠注射液治疗急性脑梗死疗效显著,安全性高。
Objective To investigate the clinical efficacy and safety of butylphthalide and sodium chloride injection in the treatment of acute cerebral infarction. Methods 64 patients with acute cerebral infarction were randomly divided into control group and treatment group, 32 cases in each. Both groups were given conventional treatment, the treatment group on the basis of plus butylphthalide sodium chloride injection treatment. Clinical efficacy and neurological deficit scores (NIHSS score) changes and adverse reactions were compared between the two groups. Results After treatment, the NIHSS score of the treatment group was significantly lower than that of the control group (P <0.05). The clinical efficacy of the treatment group was significantly better than that of the control group (P <0.01). There was no significant difference in adverse reactions between the two groups (P> 0.05 ). Conclusion Butylphthalide and sodium chloride injection in the treatment of acute cerebral infarction has obvious curative effect and high safety.