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本文报告用人肝癌组织提取的肝癌酸性铁蛋白(HCCAF)为抗原建立的HCCAF放射免疫测定法,及用此法测定的正常人、原发性肝癌病人和对照组共500例的血清HCCAF值.结果表明,原发性肝癌病人的血清HCCAF值明显高于正常人及其他对照组(P<0.01),测定血清HCCAF值诊断原发性肝癌的敏感率为70.68%,特异性为95.77%.本法灵敏度高,稳定可靠,重复性好,操作简便,为临床诊断原发性肝癌提供了一项实用可靠的方法.
This article reports the HCCAF radioimmunoassay using human hepatocellular carcinoma acid ferritin (HCCAF) extracted from human hepatocellular carcinoma as an antigen, and serum HCCAF values of 500 cases of normal people, primary liver cancer patients, and control groups measured by this method. It was shown that the serum HCCAF value of patients with primary liver cancer was significantly higher than that of normal and other control groups (P<0.01). The sensitivity of the determination of serum HCCAF value in the diagnosis of primary liver cancer was 70.68%, and the specificity was 95.77%. High sensitivity, stable and reliable, good repeatability, easy operation, provide a practical and reliable method for clinical diagnosis of primary liver cancer.