许多70岁以上的老年人,常因口腔或其他慢性炎症,每日口服少量抗生素如1～2片四环素或土霉素。日久他们会出现腹泻症状,程度轻重不一,起初多不在意,但其中高达40％患者后来突然出现假膜性肠炎,死亡率极高。这就是因为口服抗生素的使用造成肠道菌群失调,使原本在正常情况不能致病的难辨梭状芽孢杆菌变为致病菌,并大量繁殖,其 Many elderly people over the age of 70, often oral or other chronic inflammation, daily oral administration of a small amount of antibiotics such as 1 or 2 tetracycline or oxytetracycline. In time, they may have symptoms of diarrhea, varying in severity, initially at the expense of more than 40% of whom subsequently developed pseudomembranous colitis with a high mortality rate. This is because the use of oral antibiotics caused by intestinal flora, so that in normal circumstances can not be caused by pathogenic Clostridium difficile bacteria, and a large number of breeding, its