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去除移植物内 T 淋巴细胞,可减少同种骨髓移植(BMT)后的移植物抗宿主病(GVHD),但又使移植物排斥反应和白血病复发增加。作者在80例白血病作了经对流离心去除移植物淋巴细胞的 HLA 相合的同种 BMT。
Removal of intra-plant T lymphocytes reduces graft-versus-host disease (GVHD) following allogeneic bone marrow transplantation (BMT), but increases allograft rejection and relapse of leukemia. The authors made an HLA-compatible allogeneic BMT of 80 leukemias that had been removed by convection centrifugation of allograft lymphocytes.