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自1965—1985.6中山眼科中心眼科医院共对3162眼施行角膜移植。最常见的角膜移植的适应症依次排列是:单纯疱疹角膜炎(活动期与静止期),细菌或真菌性角膜溃疡(炎症期或疤痕期),化学伤与热烧伤和蚕蚀性角膜溃疡,以上共占角膜移植总数的85.9%。比较少的是外伤性角膜白斑、角膜营养不良与变性。大泡性角膜病变、圆锥角膜等极为少见。从1965年至1974年,在穿透性角膜移植的病例中,细菌或真菌角膜溃疡(炎症期或疤痕期)占45.3%-68.4%;自1975年以后,其所占比例明显下降,至最近五年只占26%。与此相反,单纯疱疹角膜炎所占比例则逐年上升,至1976年以后,占穿透性角膜移植病例的45.1%-45.5%。1979年前,板层角膜移植术式较常用,近五年施用板层角膜移植的病人减少,而施行穿透移植的病人增加到70%。板层角膜移植主要用于治疗或为穿透性角膜移植作准备。所以在板层移植的适应症中,蚕蚀性溃疡占首位,化学烧伤居第二,感染性的慢性角膜溃疡或后遗的角膜疤痕占第三位。1979年以前,植片的直径以5.5-6.6 mm 居多,自1980年后,较多采用7-8mm,占50.8%。本文还简述了我院用板层角膜移植治疗蚕蚀性角膜溃疡的治愈率和体会。
Since 1965-1985.6 Zhongshan Eye Center Eye Hospital on a total of 3,262 corneal transplantation. The most common indications for keratoplasty are, in order, herpes simplex keratitis (active and quiescent), bacterial or fungal corneal ulcers (inflammation or scarring), chemical and thermal burns and Mooren’s ulcer, The total number of corneal graft accounted for 85.9% of the total. Less is traumatic leukoplakia, corneal dystrophy and degeneration. Bullous keratopathy, keratoconus, etc. are extremely rare. Bacterial or fungal corneal ulcers (inflammatory or scarring) accounted for 45.3% -68.4% of cases of penetrating keratoplasty from 1965 to 1974; their proportion dropped significantly after 1975, until recently Only five years, 26%. In contrast, the proportion of herpes simplex keratitis increased year by year, accounting for 45.1% -45.5% of penetrating keratoplasty cases after 1976. Prior to 1979, lamellar keratoplasty was more common, with fewer cases being treated with lamellar keratoplasty in the recent five years, whereas the number of patients who underwent transplants increased to 70%. Lamellar keratoplasty is primarily used to treat or prepare for penetrating keratoplasty. Therefore, indications in the lamellar transplant, the first case of mucosal ulcer, chemical burns second, infectious corneal ulcers or corneal scar after the third place. Before 1979, the diameter of the graft was mostly 5.5-6.6 mm. Since 1980, the diameter of the graft has been mostly 7-8 mm, accounting for 50.8%. This article also briefly described in our hospital lamellar keratoplasty for the treatment of Mooren ulcer cure rate and experience.