本病自1892年被发现以来曾长期被认为属罕见病,国内近年报道渐多,现将经病理检查结合临床确诊的4例报告如下。病例摘要例1:男,19岁。双小腿反复出现皮下结节,有时发热,双膝关节肿胀4个月,抗风湿治疗效果不显著。查体:前额、双胫骨前及脚底散在皮下结节10余个,直径0.5～2.0cm,其浅层皮肤充血,双膝关节 The disease has long been considered as a rare disease since it was discovered in 1892. More reports have been reported in recent years in China. The 4 cases reported by pathological examination combined with clinical diagnosis are as follows. Case Summary Example 1: Male, 19 years old. Repeated subcutaneous nodules of both legs, sometimes fever, double knee swelling 4 months, anti-rheumatic effect is not significant. Physical examination: the forehead, double tibia and the soles of the feet scattered in the subcutaneous nodules more than 10, 0.5 ~ 2.0cm in diameter, the shallow skin congestion, knees