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目的研究并探讨雷贝拉唑钠与奥美拉唑三联法治疗消化性溃疡的临床效果及安全性。方法 80例消化性溃疡患者,随机分为对照组与观察组,每组40例,对照组患者采用含奥美拉唑的三联疗法进行治疗,观察组患者采用含雷贝拉唑钠的三联疗法进行治疗,观察两组患者的临床治疗效果并作对比分析。结果研究结果显示,对照组患者中愈合18例、好转16例、无效6例,观察组患者中愈合27例、好转12例、无效1例,治疗效果组间比较差异具有统计学意义(P<0.05)。结论相比奥美拉唑三联疗法,雷贝拉唑钠三联疗法能够更好的患者消化性溃疡患者的各项临床症状,促进溃疡愈合,成本较低,值得大力推广应用。
Objective To study and discuss the clinical efficacy and safety of triple therapy of rabeprazole sodium and omeprazole in the treatment of peptic ulcer. Methods Eighty patients with peptic ulcer were randomly divided into control group and observation group, 40 cases in each group. Patients in control group were treated with triple therapy including omeprazole. Patients in observation group were treated with triple therapy with rabeprazole sodium After treatment, the clinical effects of two groups were observed and compared. Results The results showed that in control group, 18 cases were cured, 16 cases improved and 6 cases failed. In the observation group, 27 cases healed, 12 cases improved and 1 case ineffective. The difference between the two groups was statistically significant (P < 0.05). Conclusion Compared with omeprazole triple therapy, rabeprazole sodium triple therapy can better treat patients with peptic ulcer clinical symptoms, promote ulcer healing, lower cost, it is worth to promote the application.