灭滴灵已用怍结肠直肠手术中的肠道抗菌剂。作者97例择期性结肠手术中观察了该药在口服和静脉注射的效果,采用前瞻性随机双盲试验进行比较。全部病人均在手术前服用新霉素5天,46例加用口服灭滴灵200 mg,一日3次,共4天;51例加用静脉滴注灭滴灵,术前缓慢滴注500 mg,以后每8小时滴注500 mg共5个剂量。总感染率为11.3%,其中 Metronidazole has been used 怍 colorectal surgery in the intestinal antibacterial agent. The authors observed the efficacy of the drug in oral and intravenous in 97 patients undergoing elective colorectal surgery and compared prospective randomized double-blind trials. All patients were taking neomycin 5 days before surgery, 46 cases plus oral metronidazole 200 mg, 3 times a day for 4 days; 51 cases plus intravenous metronidazole, preoperative slow infusion of 500 mg, after every 5 hours drip 500 mg a total of 5 doses. The total infection rate was 11.3%, of which