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目的 观察甲状腺功能减退患者血清肌酸磷酸激酶 (CK)的变化情况以及与病情的相关性。 方法 44例甲状腺功能减退症患者血清酶值与正常人对照比较 ,并与自身治疗前后相对照。 结果 甲状腺功能减退患者血清 CK、AL T、AST较正常对照组显著增高 (P<0 .0 5 )。病情控制者 ,CK、AST下降 ,并且 CK与 FT3、FT4密切相关。 结论 甲状腺功能减退可影响患者全身代谢情况 ,使组织细胞受到损伤 ,多种血清酶活性发生改变 ,与 CK关系密切。
Objective To observe the changes of serum creatine phosphokinase (CK) in patients with hypothyroidism and its relationship with the disease. Methods 44 cases of hypothyroidism patients with serum enzyme levels compared with normal controls, and compared with their own treatment before and after. Results Serum CK, ALT, AST in patients with hypothyroidism were significantly higher than those in normal control group (P <0.05). Disease controller, CK, AST decreased, and CK and FT3, FT4 are closely related. Conclusions Hypothyroidism can affect systemic metabolic status of patients, resulting in injury of tissue cells and changes of various serum enzyme activities, which are closely related to CK.