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胃泌素瘤病人手术时发现至少有60％是恶性的,其中50％已转移至肝脏,超过50％的病人是多中心或在胰腺内转移,手术切除后复发率超过50％。因此,多数学者认为,早期诊断是提高胃泌素瘤患者生存率的根本。确定一些标准对全部消化道溃疡病人进行筛选是必要的。其标准为:①正规内科治疗溃疡经久不愈;②溃疡病合并长期腹泻;③年龄小于25岁的溃疡病患者(溃疡病发病的平均年龄为34±7岁)。
At least 60% of gastrinoma patients were found to be malignant at the time of surgery, 50% of them had metastasized to the liver, and more than 50% of patients had multicenter or metastasis in the pancreas. The recurrence rate after surgical resection was more than 50%. Therefore, most scholars believe that early diagnosis is the fundamental to improve the survival rate of patients with gastrinoma. It is necessary to determine a number of criteria for the screening of all peptic ulcer patients. Its criteria are: 1 regular medical treatment of ulcers prolonged healing; 2 ulcers with long-term diarrhea; 3 patients aged less than 25 years of ulcer disease (the average age of ulcer disease is 34 ± 7 years old).