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生测结果表明，苦皮藤毒杀成分苦皮藤素Ⅴ若被试虫摄入消化道（胃毒处理），则在小地老虎Ａｇｒｏｔｉｓｙｐｓｉｌｏｎ和粘虫Ｍｙｔｈｉｍｎａｓｅｐａｒａｔａ幼虫之间有明显的选择毒杀作用：对小地老虎４龄幼虫，即使给予高达１０５ｍｇ／ｇ的剂量，试虫也不表现任何中毒症状，而对粘虫４龄幼虫，仅给予３７６μｇ／ｇ的剂量，试虫就表现失水、死亡。若直接将苦皮藤素Ⅴ注入试虫血淋巴，则小地老虎和粘虫４龄幼虫都表现相同的失水、死亡症状，不表现选择毒杀作用。这种胃毒选择毒杀作用的机理包括２个方面：①药剂在虫体内穿透作用的差异。苦皮藤素Ⅴ很容易从粘虫幼虫消化道穿透肠壁进入血腔，也容易从血腔进入消化道；但苦皮藤素Ⅴ既不能从小地老虎幼虫消化道进入血腔，也不能从血腔进入消化道；②试虫解毒能力的差异。活体试验和离体试验都说明小地老虎幼虫对苦皮藤素Ⅴ的解毒速率远大于粘虫幼虫。
Bioassay results show that the bitter pit poison poisoning component celangulin â ... ¤ if the test insects into the digestive tract (stomach poisoning treatment), there is a clear choice between the poisonous tiger A Grotisypsilon and armyworm Mythimnaseparata larvae Killing effect: The 4th instar larvae of the genus Little Tigers did not show any symptoms of poisoning even at doses up to 10 5 mg / g, whereas the fourth instar larvae of the armyworm were given only a dose of 37 6 μg / g, Insects on the performance of water loss, death. If direct injection of celangulin Ⅴ into the hemolymph of test insects, the fourth instar larvae of both the small tiger and the armyworm show the same symptoms of dehydration and death, do not show the choice of toxic effects. The mechanism of this toxic selection of gastric poisoning include two aspects: ① the penetration of pesticides in the body of the role of differences. Celangulin Ⅴ easily penetrate the intestinal wall from the armyworm larvae digestive tract into the bloodstream, but also easy to enter the digestive tract from the blood; however, celangulin Ⅴ neither from small tiger larvae digestive tract into the blood cavity, nor From the blood into the digestive tract; ② test detoxification capacity difference. In vivo tests and in vitro tests indicate that the rate of detoxification of celangulin Ⅴ in Larvae Larvae is much greater than that of armyworm larvae.