人巨细胞病毒(Human Cytomegalovirus,HCMV)感染在不同人群中普遍存在,多为无症状感染或潜伏感染,一旦免疫机能减弱或缺陷时,则引起严重疾病,在胎儿和新生儿可致严重损害,包括小头畸形,生长发育迟缓,智力障碍和感觉神经性耳聋等,在器官移植、艾滋病及其它免疫缺陷患者可增加病死率和移植器官排斥率。因此,巨细胞 Human Cytomegalovirus (HCMV) infection is prevalent in different populations, most of which are asymptomatic or latent infection. Once the immune function is weakened or defective, it causes serious diseases and can cause severe damage in the fetus and newborn, Including microcephaly, growth retardation, mental retardation and sensory nerve deafness, etc., in organ transplantation, AIDS and other immunodeficiency patients can increase mortality and rejection rate of transplanted organs. So giant cells