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目的客观评价早期应用糖皮质激素治疗小儿过敏性紫癜消化道出血的临床疗效与安全性。方法将本院68例过敏性紫癜消化道出血患儿随机分为两组,对照组给予止血敏治疗,观察组采取甲泼尼龙静脉冲击治疗,对比两组临床疗效与安全性。结果观察组显效率与总有效率均优于对照组,消化道出血停止时间显著短于对照组;两组均未见明显不良反应。结论糖皮质激素治疗小儿过敏性紫癜消化道出血疗效可靠,安全性高,值得临床推广。
Objective To objectively evaluate the clinical efficacy and safety of early application of glucocorticoid in the treatment of gastrointestinal bleeding in children with Henoch-Schonlein purpura. Methods 68 cases of allergic purpura digestive tract bleeding in our hospital were randomly divided into two groups, the control group given hemostatic treatment, the observation group to take methylprednisolone pulse therapy, the clinical efficacy and safety of the two groups were compared. Results The effective rate and total effective rate of the observation group were better than that of the control group, and the stopping time of gastrointestinal bleeding was significantly shorter than that of the control group. No obvious adverse reactions were observed in both groups. Conclusion glucocorticoid treatment of children with Henoch-Schonlein purpura gastrointestinal bleeding reliable, safe, worthy of clinical promotion.