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摄入亚硝酸盐和仲胺在胃内可形成有致癌性的亚硝胺,但其形成受到体内外各种物质的制约,如硫氰酸盐、碘化物和溴化物能催化亚硝胺的形成,而维生素C、鞣酸、尿素和硫酸胺则可抑制亚硝胺的形成。为此,本文作者研究了苯酚抗氧化剂对亚硝酸盐和二甲基胺在大鼠胃内形成亚硝胺的作用。作者以125mg/kg亚硝酸钠及1,000mg/kg二甲
Intake of nitrite and secondary amine in the stomach can form a carcinogenic nitrosamines, but its formation by various in vitro and in vivo constraints, such as thiocyanate, iodide and bromide can catalyze the nitrosamines Formation, and vitamin C, tannic acid, urea and amine sulfate can inhibit the formation of nitrosamines. To this end, the authors studied the effect of phenol antioxidants on the formation of nitrosamines in the rat stomach by nitrite and dimethylamine. The author of 125mg / kg sodium nitrite and 1,000mg / kg dimethyl