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目的分析了解原发性胆囊癌的临床特点。方法总结分析110例原发性胆囊癌患者的临床表现、影像学特点、诊断和治疗情况。结果胆囊癌患者早期诊断率为8.2%(9/110);女63例,男47例;年龄31～80岁,平均年龄57.3岁。临床表现无特异性,诊断主要依靠影像学检查。110例患者均首先行B超检查,其中57例再行CT检查,23例行MRI检查。110例患者中,57例行根治性切除术,41例行姑息性切除术。88例患者获随访,术后生存期15 d至5年11个月,中位生存期为6.5个月。结论原发性胆囊癌患者早期诊断率低,预后差,病史和影像学检查是诊断胆囊癌的重要依据。
Objective To analyze and understand the clinical features of primary gallbladder cancer. Methods The clinical manifestations, imaging features, diagnosis and treatment of 110 patients with primary gallbladder cancer were analyzed. Results The early diagnosis rate of gallbladder cancer was 8.2% (9/110). There were 63 females and 47 males, ranging in age from 31 to 80 years with a mean age of 57.3 years. No specific clinical manifestations, the diagnosis depends mainly on imaging studies. All 110 patients underwent B-mode ultrasonography first, in which 57 cases underwent CT and 23 cases underwent MRI. Of the 110 patients, 57 underwent radical resection and 41 underwent palliative resection. Eighty-eight patients were followed up for a median follow-up of 15 days to 11 years and a median survival of 6.5 months. Conclusion The early diagnosis rate of patients with primary gallbladder cancer is poor, and the prognosis is poor. The history and imaging examination are important bases for the diagnosis of gallbladder cancer.