论文部分内容阅读
目的探讨利奈唑胺治疗意识障碍致吸入性肺炎的临床疗效。方法选取长阳土家族自治县人民医院2011年7月—2015年9月收治的意识障碍致吸入性肺炎患者70例,按照随机数字表法分为对照组和治疗组,各35例。两组均给予基础的抗菌药物治疗,对照组给予替考拉宁治疗,治疗组给予利奈唑胺治疗,比较两组患者的临床疗效、症状消失时间、总病程及不良反应发生情况。结果治疗组治疗总有效率为91.4%(32/35),高于对照组的71.4%(25/35),差异有统计学意义(P<0.05);治疗组呼吸困难消失时间、正常体温恢复时间、病灶吸收好转时间、肺部体征消失时间及总病程均短于对照组,差异有统计学意义(P<0.05);两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论利奈唑胺治疗意识障碍致吸入性肺炎临床疗效显著,值得推广应用。
Objective To investigate the clinical efficacy of linezolid in the treatment of aspiration pneumonia caused by disturbance of consciousness. Methods Seventy patients with consciousness-induced aspiration pneumonia admitted from July 2011 to September 2015 in Changyang Tujia Autonomous County People’s Hospital were divided into control group and treatment group according to random number table. The two groups were given basic antimicrobial treatment. The control group was treated with teicoplanin. The treatment group was treated with linezolid. The clinical efficacy, the disappearance of symptoms, the duration of the symptoms and the incidence of adverse reactions were compared between the two groups. Results The total effective rate of the treatment group was 91.4% (32/35), which was higher than that of the control group (71.4%, 25/35) (P <0.05). The treatment group had no recovery of dyspnea, normal body temperature Time, improvement of lesion absorption time, disappearance of lung signs and the total duration of disease were shorter than the control group, the difference was statistically significant (P <0.05); two groups of adverse reaction rates, the difference was not statistically significant (P> 0.05) . Conclusion linezolid treatment of consciousness caused by aspiration pneumonia clinical significant effect, it is worth promoting the application.