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目的探讨住院胰岛素强化治疗患者低血糖发生的原因及其干预措施。方法选择内分泌科住院行胰岛素强化治疗的48例糖尿病合并低血糖患者为研究对象,通过5点血糖监测,对低血糖高发时点及低血糖发生相关因素进行观察分析。结果 48例患者发生的63次低血糖中,以空腹血糖发生频率最高,饮食因素、不适宜运动、医疗护理措施不当(医源性)等是低血糖发生常见诱发因素,胰岛功能差、高龄、肝肾功能损害及妊娠糖尿病患者是高危人群。结论加强对高危人群血糖监测和病情观察,及早识别低血糖诱发因素,采取积极防范措施,有利于减少胰岛素强化治疗患者低血糖的发生。
Objective To investigate the causes and interventions of hypoglycemia in intensive insulin therapy in hospital. Methods Forty-eight patients with diabetes mellitus and hypoglycemia admitted to Department of Endocrinology undergoing intensive insulin therapy were enrolled in this study. Five-point glucose monitoring was used to investigate the incidence of hypoglycemia and the related factors of hypoglycemia. Results Among the 63 hypoglycemic episodes in 48 patients, the most frequent cause of hypoglycemia was the incidence of fasting blood glucose, dietary factors, inappropriate exercise, inadequate medical care (iatrogenic), poor islet function, Liver and kidney dysfunction and gestational diabetes are at high risk. Conclusion It is beneficial to reduce the incidence of hypoglycemia in patients with intensive insulin therapy by strengthening the monitoring of blood glucose and the observation of the disease in high-risk groups. Identifying the factors leading to hypoglycemia as soon as possible and taking active precautionary measures.