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不少研究结果证明,患肠癌、卵巢癌、乳腺癌等时,若肿瘤组织中 DNA 含量出现不规则多倍体,常提示肿瘤易扩散或转移,预后较差。迄今头颈部鳞癌在这方面的研究资料尚少。作者对17例头颈部鳞癌的 DNA 含量进行研究。实验时每份标本分别经甲醛固定及新鲜组织直接制备二种方法处理后,以流式细胞计进行检测,并以7例正常舌部鳞形上皮作对照。流式细胞计能将制备后的细胞,通过激光照射,发出萤光,经过电子计算机的处理,绘出 DNA 含量的
Many studies have shown that, when suffering from colorectal cancer, ovarian cancer, breast cancer, etc., if the tumor tissue DNA content of irregular polyploidy, often prompted the tumor to spread or metastasis, the prognosis is poor. So far, head and neck squamous cell carcinoma in this area is still little research data. The authors studied the DNA content of 17 cases of head and neck squamous cell carcinoma. During the experiment, each specimen was fixed by formalin and prepared directly by fresh tissue. After treatment by flow cytometry, 7 cases of normal tongue squamous epithelium were used as controls. Flow cytometry The prepared cells can be irradiated by laser, emit fluorescence, after the computer processing, the DNA content is drawn