This article is written to examine the newest circumstances and characteristics in the pregnancy women targeted toothpaste market. Among the marketed toothpaste for pregnant women, the main functions of basic products are to clean teeth and freshen breath. The main functions of functional products are to prevent and reduce oral inflammation, balance the oral acid-alkali environment, reduce dental acid corrosion and caries, inhibit the growth of harmful bacteria in the oral cavity, and alleviate the pain of pregnancy and vomiting. On the basis of summarizing the oral characteristics and nursing needs of pregnant women, the problems that should be paid attention to in safety and formula design in the next step of development of toothpaste for pregnant women were put forward.