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目的 研究体内、外氩氦靶向治疗对肺癌细胞的灭活作用。方法 观察氩氦刀对体外培养的肺癌细胞、实验动物及肺癌患者,治疗前后温度响应曲线、病理等方面的变化。结果 体外实验发现氩氦刀在空气 及水中均有快速降温及升温作用,在水中能快速形成冰球及融化冰球。氩氦刀对体外培养的肺癌细胞有明显的破坏作用,在人体中也证实能灭活肺癌细胞,在1个月内,肿瘤细胞呈凝固性坏死,在3个月后则被纤维组织代替。动物实验可见,氩氦刀在肌肉组织中快速形成冰球。结论 氩氦刀有快速升、降温作用,体内、外均能灭活肺癌细胞。
Objective To study in vivo and in vitro argon helium targeted therapy of lung cancer cells inactivation. Methods The changes of temperature response curve and pathology of argon-helium knife on lung cancer cells, experimental animals and lung cancer cells cultured in vitro and before and after treatment were observed. Results In vitro experiments found that Argon-Helium Knife in the air and water have rapid cooling and warming effect, the rapid formation of ice in the water and melting ice hockey. Argon-helium knife on cultured lung cancer cells have a significant role in the destruction of the human body also confirmed that inactivation of lung cancer cells within 1 month, the tumor cells were coagulation necrosis, 3 months after being replaced by fibrous tissue. Animal experiments show that argon-helium knife in the rapid formation of muscle hockey pucks. Conclusion Argon-helium knife has a rapid rise and cool, lung cancer cells in vitro and in vivo can be inactivated.