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血吸虫成虫31/32kDa蛋白除具有公认的免疫学诊断价值外,作为疫苗抗原的候选分子也有潜在价值[1]。我们对编码大陆株日本血吸虫32kDa天冬酰胺肽链酶(Sj32)进行了克隆、测序鉴定、构建真核表达载体,并在小鼠骨骼肌细胞得到表达,为该抗原的DNA疫苗研
In addition to its well-recognized immunological diagnostic value, adult schistosomes 31 / 32kDa proteins have potential value as candidates for vaccine antigens [1]. We cloned and sequenced the 32kDa asparagine peptide chain enzyme (Sj32) encoding Schistosoma japonicum, and constructed the eukaryotic expression vector, which was expressed in mouse skeletal muscle cells. The DNA vaccine of this antigen