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目的:观察莫沙必利联合聚乙二醇电解质散治疗慢性功能性便秘的临床疗效。方法:选取我院自2015年7月-2016年8月收治的64例慢性功能性便秘患者作为观察对象,将单一接受莫沙必利治疗的32例患者设置为对照组,将接受莫沙必利联合聚乙二醇电解质散治疗的32例患者设置为观察组,观察并对比2组疗效情况。结果:观察组治疗总有效率高达96.88%(31/32),明显高于对照组的59.38%(19/32)(P<0.05);观察组疗效起效时间为服药后1~2d,平均为(1.45±0.15)d,对照组疗效起效时间为服药后4~6d,平均为(4.91±0.89)d,观察组明显短于对照组(P<0.05)。结论:针对慢性功能性便秘患者,对其采取莫沙必利联合聚乙二醇电解质散治疗,具有疗效好、见效快的优点,加上不良反应少,具有较高的临床推广价值。
Objective: To observe the clinical efficacy of mosapride combined with polyethylene glycol electrolyte powder in the treatment of chronic functional constipation. Methods: Sixty-four patients with chronic functional constipation who were treated in our hospital from July 2015 to August 2016 were enrolled in this study. Thirty-two patients receiving single mosapride as a control group were enrolled in the study. 32 patients with Polyethylene Glycol Electrolyte Powder were treated as the observation group, and the curative effect was observed and compared between the two groups. Results: The total effective rate in the observation group was 96.88% (31/32), significantly higher than that in the control group (59.38%, 19/32) (P <0.05). The observation group had an effective time of 1 ~ (1.45 ± 0.15) d, the effective time of the control group was 4 ~ 6 days after taking the drug, the average was (4.91 ± 0.89) d, the observation group was significantly shorter than the control group (P <0.05). Conclusion: For patients with chronic functional constipation, taking mosapride combined with polyethylene glycol electrolyte powder treatment has the advantages of good curative effect and quick response, plus few adverse reactions and high clinical popularization value.