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米非司酮(mifepristone)是一种有效的抗黄体酮和抗糖皮质激素药物,并有温和的抗雄激素作用。它对黄体酮有竞争性抑制作用,在受体水平可逆性阻断黄体酮对生殖系统的生物效应。据此,作者研究了米非司酮对妊娠和非妊娠宫颈的扩张和软化作用。
Mifepristone is a potent anti-progesterone and anti-glucocorticoid drug with a mild anti-androgenic effect. It has a competitive inhibitory effect on progesterone and reversibly blocks the biological effects of progesterone on the reproductive system at the receptor level. Accordingly, the authors studied the expansion and softening effects of mifepristone on pregnant and nonpregnant cervix.