Background:Photoselective vaporization of the prostate is a technique that is widely used for the treatment of benign prostatic hyperplasia (BPH) and has pronounced advantages compared to the traditional transurethral resection of the prostate.Following the recent introduction of end-firing lithium triborate lasers,we have created a new technique called photoselective vaporesection of the prostate (PVRP).This study described our initial experience using the PVRP technique for the treatment of BPH.Methods:This prospective study included a total of 35 patients with BPH who underwent PVRP from August 2013 to July 2014.The chief clinical parameters were obtained and evaluated during the perioperative period and follow-up,including the Intational Prostate Symptom Score (IPSS),quality of life (QoL) score,maximum urinary flow rate,and prostate volume.All variables were evaluated for statistically significant differences compared to baseline values using the analysis of variance.Results:The mean subgroup IPSS and QoL scores significantly improved during follow-up;the respective decreases in IPSS storage score,IPSS voiding score,IPSS nocturia score,and QoL score were 75.3％,83.6％,51.4％,and 71.7％,respectively (all P ＜ 0.001 compared with baseline).Three patients were diagnosed with prostate cancer based on postoperative pathological examinations.There were no serious perioperative complications.Conclusion:The PVRP technique demonstrates satisfactory short-term clinical outcomes and perioperative safety in the treatment of BPH.