论文部分内容阅读
目的 为了加强对鼻腔鼻窦少见的非上皮性恶性肿瘤的认识 ,对其临床特征、病理学特征进行讨论。方法 采用HE染色及免疫组化明确病理诊断后 ,进行治疗并随访。结果 经 1～ 8年随访观察 ,存活 2～ 8年 10例 ,其中恶性黑色素瘤 3例 ;非霍奇金淋巴瘤、恶性纤维组织细胞瘤各 2例 ;浆细胞瘤、横纹肌肉瘤和神经源性肉瘤各 1例。结论 这类肿瘤生长速度快 ,恶性程度高 ,易发生转移及侵犯周围器官 ,难于手术彻底切除 ,5年生存率低 ,免疫组化有助于诊断及鉴别诊断。
Objective To discuss the clinical features and pathological features of non-epithelial malignant tumors that are rare in nasal sinuses. Methods HE staining and immunohistochemistry were used to confirm the pathological diagnosis, followed by treatment and follow-up. Results After 1 to 8 years of follow-up, 10 patients survived from 2 to 8 years, of which 3 were malignant melanoma, 2 were non-Hodgkin’s lymphoma and 2 were malignant fibrous histiocytoma. Plasmacytoma, rhabdomyosarcoma and neurogenic Sarcoma in 1 case. Conclusion These tumors are characterized by high growth rate, high malignant degree, easy metastasis and invasion to surrounding organs, difficult to complete resection by surgery, and low 5-year survival rate. Immunohistochemistry is helpful for diagnosis and differential diagnosis.