目的研究心肌梗死(AMI)病人T波交替变异性(TWA)与心脏功能及其他因素的关系。方法对41名AMI病人进行TWA导联数目,左室射血功能(LVEF),磷酸肌酸激酶心肌同工酶(CK-MB)检测,同时对临床上恶性室性心律失常(室速、室颤)的发生进行观察。根据LVEF将病人分为二组;LVEF<50%,(A组)和LVEF>≥50%(B组),比较二组各指标的差异。结果二组病人在LVEF有显著差异的情况下,A组的TWA,TWA导联数目,CK-MB峰值及达到CK-MB峰值的时间均显著高于B组,同时临床上恶性心律失常事件的发生率A组也显著高于B组。结论AMI病人的TWA与LVEF及CK-MB的释放量有密切关系,TWA和LVEF均为预测室性心律失常的有力因子,表明AMI病人的LVEF越低,易形成TWA,引发恶性心律失常。 Objective To study the relationship between T wave alternating variability (TWA) and cardiac function and other factors in patients with myocardial infarction (AMI). Methods The number of TWA leads, left ventricular ejection function (LVEF) and creatine phosphokinase (CK-MB) were measured in 41 patients with AMI. Meanwhile, the incidence of malignant ventricular arrhythmia Fibrillation) were observed. The patients were divided into two groups according to LVEF; LVEF <50%, (group A) and LVEF> 50% (group B). Results In the two groups of patients with significant differences in LVEF, the number of TWA and TWA leads, the peak of CK-MB and the peak time of CK-MB in group A were significantly higher than those in group B, while the incidence of clinical malignant arrhythmia The incidence of group A was also significantly higher than that of group B. Conclusions The TWA of AMI patients is closely related to the release of LVEF and CK-MB. Both TWA and LVEF are powerful predictors of ventricular arrhythmia. It indicates that the lower the LVEF of AMI patients, the easier the formation of TWA and the induction of malignant arrhythmias.