Objective: To evaluate objectively the clinical effect and superiority of integrated traditional Chinese and western medicine (TCM WM) in treating mid late hepatocarcinoma.Methods: The 313 patients observed were divided randomly into 3 groups, Group Ⅰ, Ⅱ and Ⅲ, they were treated with protocol TACE, protocol PEI and comprehensive conservative therapy respectively. Each group was sub divided into 2 sub groups, sub group A and B, and sub￣group As was treated coordinately with different Chinese herbal medicine, Sisheng Decoction to sub group ⅠA and ⅡA, and cinobufacin or norcantharidin to ⅢA respectively. And Chinese herbal medicine prescribed according to TCM Syndrome Differentiation was also given to all the sub group As.Results: The integrated therapy showed significant effect in treating mid late hepatocarcinoma, as it could improve significantly the clinical symptoms and signs, raise the quality of life and prolong the survival time in patients. When TCM WM cooperated with TACE, it could alleviate the toxic effect and enhance the therapeutic effect of chemotherapy. There was statistical significant difference in clinical effect between the TCM WM treated groups and the western medicine treated groups ( P <0.05).Conclusion: TCM WM therapy displays not only the action in enhancing the short term therapeutic effect of treatment in treating mid late hepatocarcinoma but also shows significant effect in enhancing long term therapeutic effect and prolonging survival time in patients. It is worth further spreading. Objective: To evaluate objectively the clinical effect and superiority of integrated traditional Chinese and western medicine (TCM WM) in treating mid late hepatocarcinoma.Methods: The 313 patients were were randomly entering into 3 groups, Group I, II and III, they were treated With protocol TACE, protocol PEI and comprehensive group of groups, each group was sub divided into 2 sub groups, sub group A and B, and sub ̄group As was treated coordinately with different Chinese herbal medicine, Sisheng Decoction to sub group IA and IIA单词, and Chinese herbal medicineprecrivation to TCM Syndrome Differentiation was also given to all the subgroup As.Results: The integrated therapy showed significant effect in treating mid late hepatocarcinoma, as it could improve significantly the clinical Symptoms and signs, raise the quality of life and prolong the survival time in patients. When TCM WM Adjuvanted with TACE, it would alleviate the toxic effect and enhance the therapeutic effect of chemotherapy. There was significant difference in clinical effect between the TCM WM treated groups and the western medicine treated groups ( P <0.05).Conclusion: TCM WM therapy displays Not only the action in enhancing the treatment the short term therapeutic effect of treatment in treating mid late hepatocarcinoma but also shows significant effect in enhancing long term therapeutic effect and prolonging survival time in patients. It is worth further spreading.