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目的观察低分子肝素对小儿肾病综合征的效果。方法将100例肾病综合征患儿随机分为观察组和对照组,每组50例。对照组给予常规治疗方法,如强的松等;观察组在其基础上加用低分子肝素治疗。比较两组患者血白蛋白、24 h尿蛋白量情况。结果治疗后两组患者尿蛋白减少,血浆白蛋白升高,且观察组明显高于对照组,差异有统计学意义(P<0.05)。结论在常规治理基础上增加低分子肝素,可以有效改善小儿肾病综合征的症状。
Objective To observe the effect of low molecular weight heparin on children with nephrotic syndrome. Methods 100 cases of nephrotic syndrome were randomly divided into observation group and control group, 50 cases in each group. The control group was given conventional treatment, such as prednisone; the observation group on the basis of plus low molecular weight heparin treatment. Compare the two groups of patients serum albumin, 24 h urinary protein situation. Results After treatment, urinary protein and plasma albumin in both groups decreased, and the observation group was significantly higher than the control group, the difference was statistically significant (P <0.05). Conclusion The addition of low molecular weight heparin on the basis of routine treatment can effectively improve the symptoms of children with nephrotic syndrome.