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为了探讨涎腺肌上皮瘤与多形性腺瘤的病理鉴别，复查了９３０例多形性腺瘤，对从中确诊的３８例肌上皮瘤进行了病理学和抗ＣＫ－１８、Ａｃｔｉｎ、Ｓ－１００蛋白抗体的免疫组化研究。结果显示：肌上皮瘤的误诊率占多形性腺瘤的４％；病理上分为上皮细胞型、梭形细胞型、浆细胞样细胞型、透明细胞型和混合细胞型，各种形态的瘤细胞可以互相转化；免疫组化显示上述三种抗体各型均呈阳性反应，每例中瘤细胞的阳性程度一致；多形性腺瘤的反应结果则不同。结果表明，明确肌上皮瘤各亚型病理特征是与多形性腺瘤鉴别的关键；免疫组化结果分析有助于两者的鉴别；对组织起源的探讨可从肿瘤分化上认识两者的不同
To investigate the pathological differentiation of salivary myoepithelial neoplasia and pleomorphic adenomas, we reviewed 930 pleomorphic adenomas and performed pathological examinations and anti-CK-18, Actin, and S-100 proteins in 38 cases of myoepithelioma diagnosed from them. Immunohistochemical study of antibodies. The results showed that the misdiagnosis rate of myoepithelioma accounted for 4% of pleomorphic adenomas; pathologically it was divided into epithelial cell type, spindle cell type, plasma cell-like cell type, clear cell type, and mixed cell type, various forms of tumor Cells can be transformed with each other; immunohistochemistry shows that all three types of antibodies are positive, and the positive degree of tumor cells in each case is the same; the results of pleomorphic adenomas are different. The results showed that the pathological features of each subtype of myoepithelial neoplasia are the key to identification with pleomorphic adenomas; the analysis of immunohistochemical results is helpful to the identification of the two; the study of the origin of tissue can distinguish the difference in tumor differentiation.