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目的探讨对十二指肠溃疡患者选择泮托拉唑药物加以治疗后获得的疗效评价结果。方法 110例十二指肠溃疡患者作为研究对象,选择抽签分组的方法分为对照组与观察组,每组55例。对照组:治疗药物为奥美拉唑(20 mg),口服频率为1次/d;观察组:治疗药物为泮托拉唑(40 mg),口服频率为1次/d。对两组患者完成4周治疗后,于临床对患者实施胃镜复查工作,最终对两组患者的溃疡愈合效果进行比较。结果治疗4周后,观察组总有效率为98.18%,高于对照组的76.36%,差异具有统计学意义(P<0.05)。两组均未表现出显著药物应用不良反应的现象。结论对于十二指肠溃疡在就诊过程中,对其具体症状表现等加以分析后,合理选择泮托拉唑药物展开疾病治疗,最终可以获得显著的溃疡愈合评价效果。
Objective To evaluate the curative effect of the treatment of pantoprazole in patients with duodenal ulcer. Methods A total of 110 patients with duodenal ulcer were enrolled in this study. The methods of random selection were divided into control group and observation group, 55 cases in each group. In the control group, omeprazole (20 mg) was administered orally at a frequency of 1 d. The observation group was treated with pantoprazole (40 mg) at a frequency of 1 d / d. After completing the four-week treatment, the two groups of patients were treated with gastroscopy in clinical practice, and finally the ulcer healing effect was compared between the two groups. Results After 4 weeks of treatment, the total effective rate in the observation group was 98.18%, which was higher than that in the control group (76.36%), the difference was statistically significant (P <0.05). No adverse drug reactions were observed in either group. Conclusions For the treatment of duodenal ulcer during the course of treatment, the specific symptoms of the duodenal ulcer were analyzed. After the treatment of the disease with pantoprazole was reasonably selected, the ulcer healing evaluation could be finally obtained.