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目的:观察西沙比利治疗早产儿喂养不耐受的疗效。方法:将早产喂养不耐受患儿80例随机分为治疗组和对照组各40例。患儿入院后给予保暖、氧疗、胃肠喂养,适量静脉营养补充其入量不足,进食后半卧位;治疗组在此基础上给予西沙比利0.3 mg/(kg.次),1次/8~12 h,观察两组患儿的疗效。结果:治疗组总有效率(82.5%)优于对照组(62.5%),两组比较差异有统计学意义(P<0.05)。结论:西沙比利可加速胃排空,促进肠道蠕动,恢复胃肠功能,治疗早产儿喂养不耐受疗效显著,未见不良反应发生。
Objective: To observe the effect of cisapride on feeding intolerance in premature infants. Methods: 80 cases of infants with premature feeding intolerance were randomly divided into treatment group and control group of 40 cases. Children admitted after admission to give warm, oxygen therapy, gastrointestinal feeding, adequate amount of intravenous nutrition to supplement its intake, semi-recumbent after eating; treatment group on this basis given cisapride 0.3 mg / (kg.), 1 / 8 ~ 12 h, observed the efficacy of two groups of children. Results: The total effective rate (82.5%) in the treatment group was superior to that in the control group (62.5%). There was significant difference between the two groups (P <0.05). Conclusion: Cisapride can accelerate gastric emptying, promote intestinal peristalsis, restore gastrointestinal function, treat premature infants with intolerance significantly, and no adverse reactions occurred.