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目的:评价高敏感C反应蛋白与冠状动脉病变严重程度的相关性,为临床诊疗提供依据。方法:对入选者进行冠状动脉造影,根据造影结果将入选者分为四组,用Gensini积分方法对冠状动脉病变程度进行积分,采用免疫速率散射比浊法测定各组血浆中高敏感C-反应蛋白(hs-CRP)含量,研究hs-CRP与冠状动脉病变程度的关系。结果:与对照组相比,单支病变组、双支病变组及三支病变组,血浆hs-CRP显著增加。结论:hs-CRP与冠状动脉造影病变程度一致,检测hs-CRP可预测冠状动脉病变的严重程度。
Objective: To evaluate the correlation between high sensitivity C-reactive protein and the severity of coronary artery disease, and to provide evidence for clinical diagnosis and treatment. Methods: The coronary angiography was performed on the enrolled subjects. According to the results of radiography, the enrolled patients were divided into four groups. The degree of coronary artery lesion was determined by Gensini integral method. The plasma high sensitive C-reactive protein (hs-CRP) levels, the study of hs-CRP and the severity of coronary artery disease. Results: Compared with the control group, plasma hs-CRP levels were significantly increased in the single-vessel disease group, double-vessel disease group and triple-vessel disease group. Conclusion: The hs-CRP is consistent with coronary angiography. The detection of hs-CRP can predict the severity of coronary artery disease.