左氧氟沙星与维生素C注射液的配伍稳定性

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目的 :考察室温下 8h内 ,左氧氟沙星注射液与维生素C配伍稳定性。方法 :采用紫外分光光度仪测定配伍后 0~ 8h内左氧氟沙星的含量变化 ,紫外吸收光谱的变化及稳定性。结果 :室温下 8h内 ,左氧氟沙星注射液与维生素C配伍后外观、含量、pH均无显著变化。 结论 :8h内左氧氟沙星注射液与维生素C配伍基本稳定 Objective: To investigate the stability of compatibility of levofloxacin and vitamin C in 8h at room temperature. Methods: The content of levofloxacin, the change of ultraviolet absorption spectrum and its stability in 0 ~ 8h after compatibility were determined by ultraviolet spectrophotometer. Results: There was no significant change in the appearance, content and pH of levofloxacin injection in combination with vitamin C at room temperature within 8 hours. Conclusion: The compatibility of levofloxacin and vitamin C is stable within 8h
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