近来的证据提示,血管内凝血对许多疾病的症状发生可能起着重要作用。凝血障碍可为急性或慢性,局限或弥散,且血管内凝血的症状体微可发生在基础疾病的活动期或静止期。有些人曾经发现癌症病人常有临床症状不显的血管内凝血,表现为凝血蛋白的异常、纤维蛋白分裂产物的增高、血小板或纤维蛋白元的消耗增加。作者的经验指出,在血管内凝血的病人中其神经症状体微可出现在由其他系统的体徵或实验室检查作出诊断之前。本文的目的在于提示,在某些临床实践中一组特殊的神经症状体徵可预示发生了血管内凝血,从而使人们可以 Recent evidence suggests that intravascular coagulation may play an important role in the development of the symptoms of many diseases. The coagulopathy can be acute or chronic, localized or diffuse, and symptomatic microvascular coagulation can occur during the active or quiescent phase of underlying disease. Some people have found that cancer patients often have clinical symptoms are not obvious intravascular coagulation, manifested as abnormalities in coagulation proteins, increased fibrin cleavage products, increased platelet or fibrin unit consumption. The authors’ experience states that neurological symptoms can occur in patients with intravascular coagulation before they are diagnosed by other systemic signs or laboratory tests. The purpose of this article is to suggest that in some clinical practice a set of specific signs of neurological symptoms may predict the occurrence of intravascular coagulation so that one can