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采用与chandler氏相似的方法,制取家兔体外人工红、白血栓,然后分别注入同体家兔颈静脉,使之形成肺循环红、白血栓。在48小时内,给予实验动物某种活血化瘀中药或对照生理盐水。结果表明,冠心Ⅱ号针剂、川芎嗪以及益母草提取物均使家兔体内红血栓的溶解率显著升高,但白血栓溶解率则未见显著升高。结果说明活血化瘀中药的作用原理可能与血栓溶解有一定联系。
Using a method similar to that of chandler’s, rabbit red and white blood clots were prepared in vitro and injected into the jugular vein of rabbits respectively to form pulmonary red and white blood clots. Within 48 hours, the experimental animals were given a certain Chinese medicine or control blood circulation of saline. The results showed that the dissolution rate of red blood clot in rabbits was significantly higher than that of coronary heart Ⅱ injection, ligustrazine and motherwort extracts, but the dissolution rate of white blood clots was not significantly increased. The results show that the principle of action of traditional Chinese medicine may have a certain relationship with thrombolysis.