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本实验证实,1-烯丙基氯-3在低浓度(0.02M-对管蛋白聚合无抑制作用;高浓度(0.163M)对管蛋白聚合有抑制作用,聚合的MT变性和数量减少,管蛋白分子量无改变。Ca~(2+)在0.125mM即可明显抑制管蛋白聚合,聚合的MT变性和数量减少与1-烯丙基氯-3所致MT异常相似。由此可见,1-
This experiment confirmed that 1-allyl chloride-3 has no inhibitory effect on tube protein polymerization at a low concentration (0.02M); tube protein polymerization is inhibited at a high concentration (0.163M); MT degeneration and quantity decrease Protein molecular weight unchanged.Ca ~ (2 +) at 0.125mM can significantly inhibit tubular protein polymerization, polymerization of MT degeneration and quantitative reduction and 1-allyl chloride-induced MT abnormalities similar to 1. Thus, 1-