论文部分内容阅读
本文报告了1974例(新生儿～75岁)武汉地区健康者和51例心血管病和脑血管病者的血清脂类和脂蛋白胆固醇水平以及随年龄增长而出现的变化。结果表明,新生儿脐血各项测定指标均低于其它各年龄组,男女间无差异。男女性别血清总胆固醇(T-C),低密度脂蛋白胆固醇(LDL-C),高密度脂蛋白胆固醇(HDL-C)水平,以及T-C/HDL-C和LDL-C/HDL-C比率则随年龄增长而增加(P<0.001)。血清HDL-C水平女性(61.9±16.9mg/dl)高于男性(58.8±17.4mg/dl)(P<0.001);T-C/HDL-C和LDL-C/HDL-C比率女性低于男性(P<0.001)。 脑血管病(CVD)患者与健康对照比较,血清HDL-C明显降低(P<0.001);T-C/HDL-C和LDL-C/HDL-C比率明显增高(P<0.001);高血压和冠心病(CHD)患者与健康对照比较无差异(P>0.05)。
This article reports the changes of serum lipids and lipoprotein cholesterol in 1974 healthy subjects (from newborns to 75 years of age) in Wuhan and 51 subjects with cardiovascular and cerebrovascular diseases and their changes with age. The results showed that the indicators of neonatal cord blood were lower than the other age groups, no difference between men and women. The levels of serum total cholesterol (TC), low density lipoprotein cholesterol (LDL-C), high density lipoprotein cholesterol (HDL-C) and TC / HDL-C and LDL-C / HDL- Increase and increase (P <0.001). The serum levels of HDL-C in women (61.9 ± 16.9 mg / dl) were significantly higher than those in men (58.8 ± 17.4 mg / dl) (P <0.001). The TC / HDL-C and LDL-C / HDL- P <0.001). Serum HDL-C was significantly lower in patients with cerebrovascular disease (CVD) than those in healthy controls (P <0.001); the rates of TC / HDL-C and LDL-C / HDL-C were significantly higher (P <0.001) Cardiac disease (CHD) patients and healthy controls no difference (P> 0.05).