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中耳胆脂瘤可分为原发性和继发性两型 ,其特征为外耳道及鼓膜上皮侵入中耳腔同时伴有听小骨及受侵区骨质的破坏吸收。目前 ,人们尚不完全清楚细胞因子导致原发性及继发性胆脂瘤病理学改变的机制。最近有报告显示 :白细胞介素 - 1α(IL- 1α)及肿瘤坏死因子-α(TNF-α)等炎症源
Middle ear cholesteatoma can be divided into two types of primary and secondary, which is characterized by external auditory canal and tympanic membrane epithelium invade the middle ear cavity accompanied by the destruction of the ossicles and bone invasion of the affected area. At present, it is not yet fully understood that cytokines cause the pathological changes of primary and secondary cholesteatoma. Recent reports have shown that inflammatory factors such as interleukin-1α (IL-1α) and tumor necrosis factor-α (TNF-α)