全身脉管炎的临床特征为血管炎引起局部或全身器官缺血。病因不明,病理复杂,分类混乱。多数学者指出,听力丧失伴有结节性动脉周围炎、类风湿性关节炎、Wegener氏肉芽肿病和巨细胞脉管炎等概为血管炎性综合征。Gussen(1977)曾报道一例迷路动脉的结节性动脉周围炎,提示这类病例的感觉神经性聋不仅由于病变直接侵犯耳蜗,还可能是由于内耳血管炎性改变所致。Zeek等发现有的病人有弥漫性小血管脉管炎,其特点为出血、渗出和中性白细胞核碎裂。这类患者多有坏死性脉管炎,预后不良。作者们认为本文病例为文献中首次报道的白细胞碎 The clinical feature of systemic vasculitis is vasculitis that causes ischemia of the local or systemic organ. Etiology is unknown, complicated pathology, classification disorders. Most scholars pointed out that hearing loss associated with nodular periarteritis, rheumatoid arthritis, Wegener’s granulomatosis and giant cell vasculitis are vasculitic syndrome. Gussen (1977) reported a case of lacrimal arteries of the lost arteries, suggesting that sensory deafness in these cases not only directly affects the cochlea due to lesions, but also may be due to inflammatory changes of the inner ear vasculature. Zeek found that some patients have diffuse small vessel vasculitis, which is characterized by bleeding, exudation and neutrophil fragmentation. Such patients have necrotizing vasculitis, poor prognosis. The authors consider this case to be the first report of leukocyte fragmentation in the literature