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化疗在晚期非小细胞肺癌(NSCLC)治疗中占有重要的地位,但是现有化疗方案已经达到“化疗疗效平台”。为了保持现有的疗效,提高肿瘤缓解率和生存期,提出了维持治疗的概念。维持治疗是指患者在完成标准的几个化疗周期且疾病得到控制后再接受的治疗,架起一二线治疗间的桥梁,维持治疗已经逐渐被认可。全文从化疗药物、靶向药物及中医中药等方面综述晚期NSCLC的维持治疗新进展。
Chemotherapy plays an important role in the treatment of advanced non-small cell lung cancer (NSCLC), but the current chemotherapy regimen has reached the level of “chemotherapy efficacy platform.” In order to maintain the existing efficacy and improve tumor remission rate and survival, put forward the concept of maintenance therapy. Maintenance treatment refers to the patient in the completion of the standard of several cycles of chemotherapy and disease control after receiving the treatment, set up a bridge between first-line treatment, maintenance treatment has been gradually recognized. The article reviews the progress of maintenance treatment of advanced NSCLC from the aspects of chemotherapeutics, targeted drugs and traditional Chinese medicine.