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目的 提高对肾移植术后巨细胞病毒 (CMV)感染的诊断和治疗技术。 方法 回顾性总结 1992年 12月～ 1998年 1月收治的 42例肾移植术后CMV感染的临床资料。 结果 42例均用丙氧鸟苷治疗 ,2 9例有效 ,其中 2 7例治愈 ,2例好转 ;余 13例无效者改用法昔洛韦 (其中 3例为加用法昔洛韦 )治疗 ,4例治愈 ,9例 (2 1% )死亡。本组 33例 (79% )对治疗有效。 结论 对肾移植术后CMV感染及时诊断 ,合理用药 (包括调整免疫抑制剂 )非常重要 ,丙氧鸟苷和法昔洛韦对CMV感染有较好的疗效。
Objective To improve the diagnosis and treatment of cytomegalovirus (CMV) infection after renal transplantation. Methods The clinical data of 42 cases of CMV infection after renal transplantation from December 1992 to January 1998 were retrospectively reviewed. Results 42 cases were treated with ganciclovir, 29 cases were effective, of which 27 cases were cured, 2 cases improved; the remaining 13 cases of ineffective use of famciclovir (including 3 cases with the addition of famciclovir) treatment, Four were cured and nine (21%) died. The group of 33 patients (79%) effective for treatment. Conclusions It is very important to timely diagnose CMV infection after kidney transplantation and to use it rationally (including adjusting immunosuppressant). Gavage and famciclovir have a good curative effect on CMV infection.